Creative Bioarray offers cell line characterization services to companies and research institutes in the areas of pharmaceuticals, tissue engineering, antibody or vaccine production. Cell Line Characterization Services can be used to identify or determine the genetic stability of a cell line (such as MCBs and WCBs) before proceeding to production or over time in culture. At Creative Bioarray, all services can be tailored to our client's specific needs. https://www.creative-bioarray.com/services/stable-cell-line-genetic-stability-testing.htm

For transgenic cell lines and transgenic animals generated via many methods, the integration site is random and in most cases not known. Integration of a transgene can disrupt an endogenous gene, potentially interfering with interpretation of the phenotype. In addition, knowledge of where the transgene is integrated is important for planning of crosses between animals carrying a conditional allele and a given Cre allele in case the alleles are on the same chromosome. When the transgene insertion site is unknown, zygosity is determined by expensive quantitative PCR-based approach. These limitations often force investigators to maintain transgenic models or cell lines in a hemizygous state, which may lead to less than desired expression levels of the transgene and make it less efficient and more costly. Fluorescence in situ hybridization (FISH) is a powerful technique that can be used to visualize transgene integration sites and provide a better understanding of transgene behavior. https://www.creative-bioarray.com/Services/transgene-mapping.htm

Inflammation and autoimmune is a physiological phenomenon by which the white blood cells and the substances they produce to against foreign organisms (such as bacteria and viruses). However, in some cases, the immune system can also trigger an inflammatory response without foreign invasion. In these inflammation and autoimmune diseases, the tissues are often damaged by their own immune systems. And the whole body reacts as if it were infected by a foreign organism. https://www.creative-bioarray.com/services/inflammation-and-autoimmune-disease-models.htm

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Osteoblast Cells are the key functional cells in the process of bone formation. During this process, Osteoblast cells are responsible for the synthesis, secretion and mineralization of bone matrix. Creative Bioarray’s osteoblast cells are derived from human bone. These cells are ready to be used on the research of bone development and in vitro/vivo cell based drug studies etc. In addition, they provide multiple types of Osteoblast Growth Medium Supplement Kit, Osteoblast Growth Basal Medium, Recombinant Human Periostin and osteoblast specific factor for related research. https://www.creative-bioarray.com/filter/osteoblast-cell-and-media-22.html

Pericytes are vascular mural cells embedded in the basement membrane of blood microvessels. They extend their processes along capillaries, pre-capillary arterioles and post-capillary venules. Pericytes regulate blood-brain barrier (BBB) permeability, angiogenesis, clearance, cerebral blood flow (CBF), neuroinflammation and stem cell activity. https://www.creative-bioarray.com/filter/pericytes-105.html

Custom probe synthesis will be considered completed only after you have received an optimized solution appropriate for your laboratory, clinical or research projects. Finally, we will help you to adjust use protocols for unconventional or challenging sample types, such as dense or calcified tissues, complex biological fluids, or specimens derived from unconventional fixing protocols or cell spreads. https://www.creative-bioarray.com/services/fish-probe-design-synthesis-and-testing-service.htm